Endocrine Abstracts

A 24-year-old female make-up artist presented with a 6 months history of emotional lability, heat intolerance, weight loss and shaking of the hands. She described a deteriorating relationship with her spouse and increasing difficulties performing her professional role. On examination, she demonstrated marked agitation, tremor, sweating and tachycardia. Biochemistry confirmed severe thyrotoxicosis (fT4 84 pmol/l, TSH<0.01 mU/l). Subsequent clinic attendance and c...

Bilateral adrenal haemorrhage is an uncommon but life-threatening condition which may result from trauma, sepsis, coagulopathy, underlying tumour or autoimmune conditions. We present a 62-year-old female with a history of well controlled hypertension and asthma who was admitted with sudden onset epigastric pain and suspected cholecystitis. She received her first dose of Astrazeneca (AZ) Covid-19 vaccine seven days prior to onset of symptoms. Her systolic blood pressure was mor...

Background: The BTA guidelines for the use of thyroid function tests recommend the measurement of TSH receptor antibodies (TRAb) when investigating hyperthyroidism of uncertain aetiology, in suspected Graves’ ophthalmopathy and in pregnant women with Graves’ disease. An in-house TSH receptor autoantibody ELISA assay (TRAb) was introduced in 2008. This study has audited the assay performance and evaluated its clinical usefulness in a tertiary centre.<p class="abst...